Fritz J Sedlazeck (Group Leader)

Research

I am a computational Biologist focusing on method developing for sequencing applications.
In general, my interests focus on three key areas:

  1. Sequence Analysis:
    • Method development to analyze Next Generation Sequencing (NGS) data
    • Detection of Structural Variations
    • Assessment of the variability of genomes
  2. High performance computing:
    • Programming on GPU Graphics Cards (CUDA, OpenCL)
    • Programming on CPUs (SSE, AVX)
    • Programming on Grid Engine (SGE, Slurm)

Education

  • B.S. / Dipl. Ing. (FH) in Bioinformatics, Upper Austria University of Applied Sciences, Hagenberg, 2008
    • Thesis: Correlative Cryo-Fluorescence and Cryo-Electron Microscopy
  • Ph.D / Dr. rer. nat. in Bioinformatics, University of Vienna, 2012
    • Thesis: Benchtop Sequencing on Benchtop Computers
  • Workshop on supervised learning, University of Washington, 2016
  • Workshop on unsupervised learning, University of Washington, 2016

Work experience

  • 08/2007-01/2008: Internship
    • The European Molecular Biology Laboratory
    • Duties included: Method development for cryo electron microscopy
    • Supervisor: Achilleas Frangakis
  • 11/2008-12/2012: PhD student
    • Cibiv - Max F. Perutz Laboratories
    • Duties included: Method development for NGS and SVs detection
    • Supervisor: Arndt von Haeseler
  • 01/2013-12/2014: PostDoc
    • Cibiv - Max F. Perutz Laboratories
    • Duties included: Method development for NGS and SVs detection
    • Supervisor: Arndt von Haeseler
  • 12/2014-12/2015: Computational Sci. Analyst I
    • Simons Center for Quantitative Biology - Cold Spring Harbor Laboratories
    • Duties included: Method development for NGS and SVs detection
    • Supervisor: Michael C. Schatz
  • 12/2015-04/2017: PostDoc
    • Department of Computer Science - Johns Hopkins University
    • Duties included: Method development for NGS and SVs detection
    • Supervisor: Michael C. Schatz
  • 04/2017-present: Lead Scientific Programmer
    • HGSC, Baylor College of Medicine
    • Duties included: Method development for NGS and SVs detection

Reviewing

Genome Research, Nature Communications, GigaScience,Heredity, BMC Genomics, RECOMB 2016, BMC Bioinformatics, Oxford Bioinformatics, PLOS ONE, Molecular Biology and Evolution, PeerJ, Cogent Biology, International Journal of Computational Science and Engineering (IJCSE)

Publications

Talks

Teaching